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Weight Management : In 2021, the FDA approved semaglutide (under the brand name Wegovy) for chronic weight management in adults with obesity or overweight with at least one weight-related condition, such as high blood pressure or type 2 diabetes

Accordingly, it is postulated that the high glutamate concentration in the intestinal microenvironment, which may reach the millimolar range, could prevent inappropriate responses to dietary antigens by exerting immunosuppressive effects on intestinal T cells (178)