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Companies that successfully address muscle preservation, reduce discontinuation-related regain, improve access and tolerability, or develop precision approaches for treatment-resistant patients will capture meaningful differentiation in what promises to become an increasingly commoditized market for first-generation GLP-1 agonists

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In this study, researchers wanted to see how tirzepatide affected the amount of fat in the liver (liver fat content or LFC), as well as the volume of fat in the belly (visceral adipose tissue or VAT) and under the skin in the abdomen (abdominal subcutaneous adipose tissue or ASAT)