Drug-substrates of large clinical importance include angiotensin-2 antagonist, nonsteroid antiinflammatory drugs (NSAIDs), oral antidiabetics, antimicrobials, antiepileptics, and oral anticoagulants (Table 1) (7,8)
420 The restrictive functions of the bloodbrain barrier (BBB) block foreign substances from entering the brain, which is the predominant reason for the lack of pathogenesis-targeting therapies
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Cognitive decline has been linked to decreased levels of docosahexaenoic acid (DHA) in the brain (164)
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The role of lithium in the treatment of bipolar disorder: convergent evidence for neurotrophic effects as a unifying hypothesis