Accessed August 2024 at These statements are provided for educational purposes only
Other contraindications and precautions for GLP-1 agonists include a history of severe allergic reactions to the medication or its components, acute or chronic pancreatitis, gallbladder disease or gallstones, and certain forms of diabetic retinopathy
Additionally, those with a history of pancreatitis are carefully assessed to ensure the treatment is safe
Neal B, Perkovic V, Mahaffey KW, et al
Exploring SGLT2 Inhibitors SGLT2 inhibitors, including empagliflozin (Jardiance), dapagliflozin (Farxiga), and canagliflozin (Invokana), offer a different therapeutic pathway
The activation of GLP-1R by a specific agonist induces an increase in intracellular cAMP levels, which leads to channel opening