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Peters C, Nicholas AK, Schoenmakers E et al (2019) DUOX2/DUOXA2 mutations frequently cause congenital hypothyroidism that evades detection on newborn screening in the United Kingdom

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Rybelsus is an oral form approved for managing blood sugar levels, while Ozempic is used via injection for the same purpose

The researchers defined 16 GLP-1RA treatment scenarios for GLP-1RA users by semi-annually reassigning their treatment status, conditional on their current use status, thereby emulating dynamic treatment strategies over time

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This titration schedule minimises gastrointestinal side effects such as nausea, vomiting, and diarrhoea