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Inhibition of DMT1 expression reduces the transport of iron, copper, and zinc into cells, suggesting that DMT1 mediates the transport of multiple metals [275]

however, only in small amounts

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Eli Lilly and Company, Sanofi, Novo-Nordisk A/S, AstraZeneca, Amgen, Inc.

When released to the circulation, the bone-derived FGF23 binds to its receptor in epithelial cells of the proximal tubules of the kidney leading to decreased expression the type II sodium-phosphate co-transporters, NPT2a (encoded by the SLC34A1 gene) and NPT2c (encoded by the SLC34A3 gene)

Cell Metab (2019) 30:93751.e5