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When bound to the lysosome surface, active ARL8-GTP directly or indirectly via association with the adaptor protein PLEKHM2/ SKIP recruits kinesins KIF1A 19,20 , and KIF5A-C 10 to promote microtubule-dependent lysosome dispersal to the cell periphery
389 The interaction between GLP-1 and its receptor GLP-1R initiates the AMPK signaling cascade within skeletal muscle tissue
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Cur-CPP liposomes significantly ameliorate apparent symptoms including erythema and silver scales, as well as epidermal thickness, in an IMQ-induced psoriasis mouse model [325]