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Patients should be counseled about the risk of dehydration and potential acute kidney injury with severe gastrointestinal symptoms, and the need to temporarily hold medication and seek care if severe vomiting or diarrhea occurs

Potential synergy with peptides related to the regulation of the GH/IGF-1 axis is discussed

Fermented foods support gut bacteria that influence digestive function

J Cutan Pathol 2006 Apr;33(4):261-79 Available from: Leibovitch I, Huilgol SC, Selva D, Hill D, Richards S, Paver R

Special Considerations Caffeine Coffee is not universally problematic on GLP-1s, but two rules matter: (1) always with food, never on an empty stomach coffee on an empty stomach triggers severe nausea in a majority of GLP-1 patients, and (2) limit to 2 cups per day

Instead of trying to piece together your day at night and realizing you have fallen short, you can make smart choices about whether to have another snack or if you've actually reached your goal