Berendsen HJC, Postma JPM, van Gunsteren WF, Hermans J (1981) Interaction Models for Water in Relation to Protein Hydration
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All these systems were discovered and extensively studied upon the realization that inflammatory responses are brought down to homeostatic levels by the active engagement of endogenous pathways rather than passively as previously believed (134)
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doi: 10.1038/nature12820 22 de VosW

Macromolecule Content Total Structure Weight: 525.75 kDa Atom Count: 34,893 Modeled Residue Count: 4,474 Deposited Residue Count: 4,824 Unique protein chains: 1 Experimental Data Method: X-RAY DIFFRACTION Resolution: 2.70 R-Value Free: 0.226 (Depositor), 0.227 (DCC) R-Value Work: 0.207 (Depositor), 0.208 (DCC) R-Value Observed: 0.208 (Depositor) Unit Cell : Software Package: Revision History (Full details and data files) Version 1.0: 2020-05-27 Type: Initial release Version 2.0: 2020-07-29 Type: Remediation Reason: Carbohydrate remediation Changes: Advisory, Atomic model, Data collection, Derived calculations, Structure summary Version 3.0: 2020-12-09 Type: Coordinate replacement Reason: Atomic clashes Changes: Advisory, Atomic model, Data collection, Database references, Derived calculations, Non-polymer description, Refinement description, Structure summary Version 3.1: 2020-12-16 Changes: Database references Version 3.2: 2024-05-15 Changes: Data collection, Database references, Refinement description
