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Building on these findings, our recent study demonstrated that sulforaphane prevented ASD-associated phenotypes induced by valproic acid, including oxidative stress, synaptic loss and neural activity disruption, highlighting sulforaphanes potential as a preventative strategy against early life ASD risk (Bessetti et al., 2025)

This manuscript gives an overview of the physiological actions of GH and IGF-1 on the kidneys and summarizes the current knowledge of their impact on kidney health in subjects with normal and impaired kidney function, including acute kidney injury (AKI), CKD and nephrotic syndrome

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98 , 99 The experiences of these individuals highlight the possibility of being resilient to Alzheimer's dementia despite genetic mutations, and point to new areas of investigation to better understand resilience