Essentially, endurance athletes may need to override their dulled thirst mechanism to avoid performance-limiting dehydration
Here, we constructed a transomic network of glucose metabolism by integrating western blotting, transcriptomic, and metabolomics data of the mouse liver following multiple doses of glucose administration
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Notably, combined approaches (e.g., structural modification + formulation optimization) can further enhance efficacy: for instance, reducing diosgenins hemolytic toxicity through cholesterol nanocomplex formation achieves integration of structural interactions and nanodelivery
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