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Description

It protects cells, detoxifies the liver, and supports the immune system

Upstream iron metabolism genes (such as FPN, TFR1, and DMT1) can influence the occurrence and development of ferroptosis 25,26,27,28 , but how does the downstream pathway change

These NADPH-generating reactions are catalyzed by MTHFD1 in the cytosol and MTHFD1L, MTHFD2L, and ALDH1L2 in the mitochondrial matrix compartment (Fig