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In hair research, the peptide is investigated for its effects on follicle size and growth cycles, partly through reducing follicle sensitivity to dihydrotestosterone (DHT) and enhancing scalp circulation and dermal papilla cell activation

Ogihara, K., Kikuchi, E., Okazaki, S., Hagiwara, M., Takeda, T., Matsumoto, K

10.1242/jcs.03062 203 NomuraS.MonobeM.EmaK.Maeda-YamamotoM.NesumiA

The total number of hairs decreased by 24.1%, the number of vellus hairs decreased by 24.4%, and the numbers of terminal hair decreased by 30.0%

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Severe loss of quality of life, due to symptoms such as debilitating fatigue, insomnia (B12 is required for synthesis of melatonin), mental illness, and neurological symptoms