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Water retention and joint stiffness from GH peptides are more pronounced in older adults

A 2022 study co-encapsulated GHK-Cu with acetyl tetrapeptide-3 and myristoyl pentapeptide-4 in nanoliposomes

Due to the decrease in GH secretion, the secretion of IGF-1, which is driven by GH release, was also drastically reduced

Commonly reported side effects are minimal and might include mild irritation or redness at the injection site