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doi: 10.1371/journal.pone.0247307

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Focusing on the safe use of compounded GLP-1 therapies allows providers to identify potential risks, educate patients using evidence-based information, and develop individualized treatment plans that prioritize both safety and trust

These effects typically intensify as the dose is gradually increased according to the prescribed titration schedule, though the delayed gastric emptying effect may attenuate with continued use

Common metabolic stressors, like a high-fat diet, can increase GLP-1 production in alpha cells but only modestly