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Mutations of SHANK2, SHANK3, NLGN4 , and NRXN1 are considered to cause ASD by altering synaptic connectivity and neuronal excitability, resulting in excitatory/inhibitory (E/I) imbalance (16)

This makes liposomal encapsulation particularly suitable for peptide hormones, enzymes, and signaling peptides that require controlled and localized action

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this region is predicted to participate in ATP-dependent channel opening [123,124]

While injectable GLP-1 receptor agonists such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) have transformed the treatment landscape for obesity and type 2 diabetes, their reliance on subcutaneous injection remains a significant barrier to broader adoption

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