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If symptoms persist beyond dose escalation, clinical review is needed to distinguish between medication effects and a separate functional bowel disorder

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It was observed that API-induced expression of caspase-3, caspase-8, CytC, and Bax proteins increased, whereas the expression of Bcl-2 decreased

Schubert CC, Boustani M, Callahan CM, Perkins AJ, Hui S, Hendrie HC

Press release, June 26, 2023

Ergnzend dazu hat die Global Leadership Initiative on Malnutrition (GLIM) ein zweistufiges Diagnoseschema entwickelt, das an das Screening anschliesst und auch eine verminderte Muskelmasse als zentrales Kriterium erfasst (37)