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Moreover, the sustained release capability of azelaic acid-loaded NLCs would be advantageous for topical drug delivery due to the prolonged localized drug deposition within the skin layers (Tangau et al., 2022)

More research is needed to know how they affect health in the long run

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Patients with contraindications - including personal or family history of medullary thyroid carcinoma or MEN 2 syndrome, pancreatitis history, severe GI or kidney disease, pregnancy, or breastfeeding - won't be approved

This happens because hormones like estrogen and testosterone drop, making it harder for the body to burn calories well