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Intrapancreatic fat deposition has been proposed to represent a key mediator of diseases of both the endocrine (i.e., type 2 diabetes) and exocrine pancreas (including PDAC and acute pancreatitis) 50

Nonetheless, these studies taken together challenge the classical idea of EEC cell types and indicate that EECs are a rare and complex class of cells that secrete peptides based largely on their location and maturation within the gut 81,84,89,90,91

De Melo Jr., MD, AGAF How do we incorporate ESD into our algorithm for management

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Summary: A Tool, Not a Magic Wand Berberine is interesting because it targets metabolic pathways and may improve some cardiometabolic markers

Some factors that could explain this connection may include: - 1