Scleroderma : Given the disease involves excessive collagen deposition, supplementation is generally not recommended without specialist guidance
In a large clinical trial of SAMe (Mato 1999), patients with alcoholic cirrhosis on SAMe (1.2 g/day for 2 years) demonstrated a non-significant trend towards improvement in 2-year survival compared to control patients
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Nat Microbiol 3:514522 Tsai ZT, Chen CL, Chiou H, Chang CJ, Chen CY, Pei-Hsuan Wu K, Chung CY, Chen PH (2024) Differential longitudinal effects of frequent sweetened food consumption at different exposure ages on child cognitive, language, and motor development
This internal cleansing of the body contributes to improved overall wellness
Although significant differences in protein levels were not found between the UFMs in the current analyses, the observation from the larger validation cohort measured by Zhi et al (1139 type 1 diabetic individuals and 848 control individuals) may have benefited from the improved statistical power