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For instance, in the presence of TiO 2 NPs, NADPH oxidase was hyper-activated, and the subsequent increase in ROS generation induced a higher level of oxidative stress (Masoud et al., 2015)

Hence, this phenomenon requires further investigation

The results showed that the Ca2+ balance was maintained in the AAV-BDNF treatment group, and that BDNF may reduce neuron apoptosis by increasing the expression of the Bcl-2 anti-apoptosis protein and inhibiting intracellular calcium overload (53)

Abstract Pyocyanin secreted by Pseudomonas aeruginosa is a virulence factor that damages epithelial cells during infection through the action of reactive oxygen species, however, little is known about its direct effect on biofilms

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