GLP-1 medications are not appropriate for people with a personal or family history of medullary thyroid carcinoma or MEN2 (Multiple Endocrine Neoplasia syndrome type 2), a history of pancreatitis, or anyone currently pregnant or breastfeeding
World J Gastroenterol 17:27232733
Tchang coauthored a review of dietary supplements and alternative therapies for weight loss, which found that none were proven to be safe and effective
Clinical trials and post-marketing surveillance have not established a direct causal relationship between these medications and night sweats
Lyophilized retatrutide, the freeze-dried powder form in which it is typically sold, demonstrates excellent stability when stored properly
GLP-1 Secretion While GLP-1 secretion was originally described in response to glucose, it also occurs with ingestion of a mixed meal and the GLP-1 response is greater than to glucose alone indicating synergy in the stimulation by fat and protein along with glucose (1, 78, 132)