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Additionally, microglia, which are primary targets of the GLP-1R signal transduction pathway in the spinal cord, exhibit reduced activation and decreased expression of pro-inflammatory cytokines following exendin-4 treatment, suggesting therapeutic potential in monophasic EAE [113]

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Glucagon-like peptide-1 (GLP-1) receptor agonistssuch as Ozempic , Wegovy , and Zepbound have become game changers for managing type 2 diabetes and weight loss

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Understanding the expected side effect timeline helps patients distinguish normal physiological responses from concerning adverse events and make informed decisions about continuing treatment

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