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Human umbilical vein endothelial cells (HUVEC, Lonza) were cultured in endothelial cell basal medium (EBM, Lonza) supplemented with endothelial cell growth medium (EGMSingleQuots, Lonza), 10% FBS, 2 mM L-glutamine, 100 U/mL penicillin and 100 g/mL streptomycin

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Tirzepatide for the treatment of obstructive sleep apnea: rationale, design, and sample baseline characteristics of the SURMOUNT-OSA phase 3 trial