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10.1083/jcb.201007013 J

Erythromelanosis follicularis faciei et colli is characterized by the triad of hyperpigmentation (darker skin color), follicular plugging (blocked hair follicles), and redness of the face and neck

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Nature 474 , 506510 (2011)

However, whether the GPX4PRDX6 interaction represents a broadly conserved ferroptosis defense mechanism or is restricted to specific cellular contexts remains to be established