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We then concentrated on the mechanistic findings related to the acceleration of depression in the context of GD, as mounting evidence has indicated that GD promotes the development of depression through various mechanisms, including triggering autoimmune responses, inducing hormonal disorders, and influencing the thyroid-gut-microbiome-brain axis
Exercise intolerance can even lead to Post-Exercise Malaise (PEM), a delayed and abnormal worsening of various symptoms and loss of energy following minimal physical or cognitive stressors or other triggers that would have been tolerated normally before disease onset (261, 262)
Loading Phase Initial period of higher-frequency dosing designed to build tissue concentrations quickly
The availability of ferritin has a direct effect on the volume of the labile iron pool
Rodent models show accelerated tendon healing, increased collagen organisation, and improved biomechanical strength under controlled injury conditions
