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Subsequent to the approval of exenatide, additional GLP-1 RAs have been FDA-approved, with differences across agents in indication for use (eg, pediatrics), route and/or intervals of administration, pharmacology, efficacy, and tolerability
Importantly, none of the mice in any of the groups displayed poor body condition score ( data not shown )
22 Finally, obesity-related comorbidities further compound reproductive risk
Also, they showed a decrease in FM and an increase in LBM, translating both findings into effects on muscle oxidative enzymes and reduction in body fat (Taaffe et al., 2001)
