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According to product information, hypersensitivity reactions are classified as uncommon (affecting less than 1 in 100 people), while anaphylaxis is rare (affecting less than 1 in 1,000 people)

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Compared with NRAS activating mutations at positions 12 and 13, NRAS Q61 mutations exert a stronger activating effect on the MAPK pathway since codon 61 is the catalytic residue for GTP hydrolysis and Q61 mutation impedes the return of RAS to an inactive GDP-bound state (92)

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Grapevine ( Vitis ) species may resist fungal infections by accumulating secondary metabolites like stilbenoid phytoalexins (trans-resveratrols)