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Altogether, initial reports of NAD + precursors and exercise in clinical trials, while encouraging in certain instances, are still too inconclusive to directly link an increase in NAD + levels and mitochondrial metabolism to established health benefits in humans
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Lifestyle interventions, including intermittent fasting and high-protein diets, can enhance natural GLP-1 production modestly but dont approach pharmaceutical potency
eBioMedicine 85 , 104311 (2022)
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