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Longer treatment durations up to several months have been examined in chronic disease models without apparent tolerance development or diminishing efficacy

coli- infected rats, zinc supplementation increased in vivo superoxide production

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Neurology 84 , 17051713 (2015)

Initial assessment: Serum B12 is measured using immunoassay techniques, with results reported in nanograms per litre (ng/L) or picomoles per litre (pmol/L)