5, May 2009, pp
MOTS-c A mitochondrial-derived peptide that may be suggested for energy, metabolism, and exercise performance
Markers of cellular senescence include increased intracellular levels of damaged and fragmented double-stranded DNA, lipofuscin, cell cycle inhibitors such as p16 and p21, and a proinflammatory secretory phenotype
Mechanistically address the question of specific receptors and signaling networks regulating ferroptosis through microbial metabolites, technically explain how to utilize organoids, multi-omics integration, and spatial transcriptomics to analyze in situ interactions, and identify biomarkers for predicting ferroptosis and microbial intervention efficacy in clinical applications (198)
Effects of Epitalon on biomarkers of aging, life span and spontaneous tumor incidence in female Swiss-derived SHR mice
Human clinical trials are scarce, and long-term safety, optimal dosing, and potential side effects remain unclear