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For H&E staining, the excised tumor and organs were fixed in 4% paraformaldehyde solution, embedded in paraffin, sectioned, and stained with H&E

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The pathway subsequently produces several neuroactive intermediate metabolites including kynurenic acid (KYNA), quinolinic acid (QUIN), 3-hydroxykynurenine (3-HK), and 3-hydroxyanthranilic acid (3HAA)

10.1055/s-0038-1676121 48 DixonS