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Kong et al

Induction of apoptosis via the extrinsic pathway is triggered by the activation of the death receptors Fas (CD95/Apo-1), TNF-related apoptosis-inducing ligand (TRAIL) receptors 1 and 2 (DR4/DR5), and TNF receptor 1 (TNFR1) by their respective ligands FasL, TRAIL, and TNF-a

Motor symptom severity, as assessed by the Movement Disorder Society-Unified Parkinsons Disease Rating Scale Part III (MDS-UPDRS III), is directly associated with TNF- levels, with higher scores corresponding to increased serum cytokine concentrations [185]

Nature 288(5792):715717

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