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In the past 12 months, three meta-analyses have appeared, covering studies until October 12 (1), December 12 (39), and February 14 (178)

When the skin barrier is compromised or when there is an imbalance in how skin cells turn over, the accumulation of keratin becomes more likely

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More noticeable effects, particularly around recovery and mobility, tend to appear after 3 to 4 weeks