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Incretin hormones, such as GLP-1 and glucose-dependent insulinotropic polypeptide (GIP), are involved in several functions such as regulating glucose levels, delaying gastric emptying, and reducing food intake [16, 17]

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Among 11 558 semaglutide-related reports, they identified 417 cases specifically related to visual impairment, retinopathy, or ischaemic optic neuropathy

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There appear to be considerable species-specificity in terms of anatomical localization of GLP-1 production as summarized in Figure 1