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JKE-1674 kills LOX-IMVI cells in a manner that is equipotent to ML-210 and is completely rescued by ferroptosis inhibitors

doi: 10.1590/1678-4685-GMB-2018-0329 129 MeloBVLAFariaSTDRLeiteKRMPimentaRCASrougiMAntunesAA

Bioactive peptides isolated from plant proteins, generally consisting of 220 amino acids, have attracted widespread attention in the academic and health care communities for their good tissue affinity, specificity, and bioactivities such as antioxidant, anti-inflammatory, and hypoglycemic properties (17, 18)

Activation of fatty acids to highly polar thiol esters, i.e., acyl-CoA, occurs on the outer mitochondrial membrane, but to enable transport across the inner mitochondrial membrane, the acyl group is transferred to carnitine with formation of acylcarnitines, which can enter the mitochondria with the assistance of translocases

10.3390/life11121311 214 zgen.SevinS

The QH-Absorb ubiquinol acts as an antioxidant to protect cardiovascular tissues while promoting cellular energy